Robert O’Hara, a talented playwright who burst into the big time with his autobiographical 2011 hit “Bootycandy,” returns to Off Broadway’s Playwrights Horizons with another high-concept dramedy called “Mankind” that boasts the same manic wit and flare for sharp-edged satire.

Unfortunately, it’s also an overlong exploration of toxic masculinity and a battle cry for women’s rights that suffers from an even more glaring shortcoming: an all-male cast.

O’Hara posits a dystopian future in which women have been rendered extinct for more than a century — at least until a careless couple of “f—mates,” played by Bobby Moreno and Anson Mount (“Hell on Wheels”), conceive a child who miraculously turns out to be a girl.

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